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Loss of muscarinic antinociception by antisense inhibition of M(1) receptors
1. The effect on cholinergic analgesia of inactivation of the M(1) gene by an antisense oligodeoxyribonucleotide (aODN) was investigated in the mouse hot plate test. Mice received a single intracerebroventricular (i.c.v.) injection of anti-M(1) aODN (0.3, 1.0 or 2.0 nmol per injection), degenerate O...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2000
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572021/ https://ncbi.nlm.nih.gov/pubmed/10780968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703268 |
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