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Loss of muscarinic antinociception by antisense inhibition of M(1) receptors
1. The effect on cholinergic analgesia of inactivation of the M(1) gene by an antisense oligodeoxyribonucleotide (aODN) was investigated in the mouse hot plate test. Mice received a single intracerebroventricular (i.c.v.) injection of anti-M(1) aODN (0.3, 1.0 or 2.0 nmol per injection), degenerate O...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572021/ https://ncbi.nlm.nih.gov/pubmed/10780968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703268 |
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