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Antagonism of nicotinic receptors of rat chromaffin cells by N,N,N-trimethyl-1-(4-trans-stilbenoxy)-2-propylammonium iodide: a patch clamp and ligand binding study
1. The effect of the oxystilbene derivative F3 was tested on nAChRs of whole-cell patch-clamped rat chromaffin cells in vitro and of rat adrenal gland membranes using (125)I-epibatidine. 2. F3 (30 nM) rapidly and reversibly blocked inward currents generated by pulse applications of nicotine, shiftin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572018/ https://ncbi.nlm.nih.gov/pubmed/10780985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703264 |
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