Characterization of a novel nonpeptide vasopressin V(2)-agonist, OPC-51803, in cells transfected human vasopressin receptor subtypes

1. We discovered the first nonpeptide arginine-vasopressin (AVP) V(2)-receptor agonist, OPC-51803. Pharmacological properties of OPC-51803 were elucidated using HeLa cells expressing human AVP receptor subtypes (V(2), V(1a) and V(1b)) and compared with those of 1-desamino-8-D-arginine vasopressin (d...

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Autori principali: Nakamura, Shigeki, Yamamura, Yoshitaka, Itoh, Shuji, Hirano, Takahiro, Tsujimae, Kenji, Aoyama, Masashi, Kondo, Kazumi, Ogawa, Hidenori, Shinohara, Tomoichi, Kan, Keizo, Tanada, Yoshihisa, Teramoto, Shuji, Sumida, Takumi, Nakayama, Sunao, Sekiguchi, Kazuo, Kambe, Toshimi, Tsujimoto, Gozoh, Mori, Toyoki, Tominaga, Michiaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571993/
https://ncbi.nlm.nih.gov/pubmed/10780976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703221
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