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Both α(1A)- and α(1B)-adrenergic receptor subtypes couple to the transient outward current (I(To)) in rat ventricular myocytes

1. Regulation of transient outward current (I(To)) by α(1)-adrenergic (α(1)AR) plays a key role in cardiac repolarization. α(1)ARs comprise a heterogeneous family; two natively expressed subtypes (α(1A) and α(1B)) and three cloned subtypes (α(1a), α(1b) and α(1d)) can be distinguished. We have exami...

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Hlavní autoři: Homma, Nobuo, Hirasawa, Akira, Shibata, Katsushi, Hashimito, Keitaro, Tsujimoto, Gozoh
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571955/
https://ncbi.nlm.nih.gov/pubmed/10725259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703179
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