Role of nitric oxide and septide-insensitive NK(1) receptors in bronchoconstriction induced by aerosolised neurokinin A in guinea-pigs

1. The tachykinin, neurokinin A (NKA), contracts guinea-pig airways both in vitro and in vivo, preferentially activating smooth muscle NK(2) receptors, although smooth muscle NK(1) receptors may also contribute. In vitro evidence suggests that NKA activates epithelial NK(1) receptors, inducing the r...

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Detalhes bibliográficos
Main Authors: Ricciardolo, Fabio L M, Trevisani, Marcello, Geppetti, Pierangelo, Nadel, Jay A, Amadesi, Silvia, Bertrand, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571918/
https://ncbi.nlm.nih.gov/pubmed/10696090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703135
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