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Role of nitric oxide and septide-insensitive NK(1) receptors in bronchoconstriction induced by aerosolised neurokinin A in guinea-pigs

1. The tachykinin, neurokinin A (NKA), contracts guinea-pig airways both in vitro and in vivo, preferentially activating smooth muscle NK(2) receptors, although smooth muscle NK(1) receptors may also contribute. In vitro evidence suggests that NKA activates epithelial NK(1) receptors, inducing the r...

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Hlavní autoři: Ricciardolo, Fabio L M, Trevisani, Marcello, Geppetti, Pierangelo, Nadel, Jay A, Amadesi, Silvia, Bertrand, Claude
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571918/
https://ncbi.nlm.nih.gov/pubmed/10696090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703135
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