Changes in the cytosolic Ca(2+) concentration and Ca(2+)-sensitivity of the contractile apparatus during angiotensin II-induced desensitization in the rabbit femoral artery

1. To investigate the underlying mechanism for the angiotensin II-induced desensitization of the contractile response during the prolonged stimulation of the vascular smooth muscle, we determined the effects of angiotensin-II on (1) cytosolic Ca(2+) concentration ([Ca(2+)](i)) and tension using fura...

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Autores principales: Ushio-Fukai, Masuko, Yamamoto, Hiromichi, Toyofuku, Kazuki, Nishimura, Junji, Hirano, Katsuya, Kanaide, Hideo
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571870/
https://ncbi.nlm.nih.gov/pubmed/10711340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703092
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