The gastric H,K-ATPase blocker lansoprazole is an inhibitor of chloride channels

1. It was postulated that swelling dependent chloride channels are involved in the proton secretion of parietal cells. Since omeprazole, lansoprazole and its acid activated sulphenamide form AG2000 are structurally related to phenol derivatives known to block swelling dependent chloride channels, we...

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Detalhes bibliográficos
Main Authors: Schmarda, Andreas, Dinkhauser, Patrick, Gschwentner, Martin, Ritter, Markus, Fürst, Johannes, Scandella, Elke, Wöll, Ewald, Laich, Andreas, Rossmann, Heidi, Seidler, Ursula, Lang, Florian, Paulmichl, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571856/
https://ncbi.nlm.nih.gov/pubmed/10711360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703070
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