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Primary porcine enterocyte and hepatocyte cultures to study drug oxidation reactions

1. Primary porcine hepatocytes and enterocytes were isolated and cultured in Williams' E medium for up to 10 days to investigate potential organ differences in the metabolism of the immunosuppressive compound tacrolimus (FK 506) and of two investigational drugs (KC11346 and KC12291). Using LC-M...

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Hlavní autoři: Bader, A, Hansen, T, Kirchner, G, Allmeling, C, Haverich, A, Borlak, J T
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571846/
https://ncbi.nlm.nih.gov/pubmed/10694240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703062
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