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Impaired relaxation of stomach smooth muscle in mice lacking cyclic GMP-dependent protein kinase I

1. Guanosine 3′, 5′-cyclic monophosphate (cyclic GMP)-dependent kinase I (cGKI) is a major receptor for cyclic GMP in a variety of cells. Mice lacking cGKI exhibit multiple phenotypes, including severe defects in smooth muscle function. We have investigated the NO/cGMP- and vasoactive intestinal pol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ny, Lars, Pfeifer, Alexander, Aszòdi, Attila, Ahmad, Marianne, Alm, Per, Hedlund, Petter, Fässler, Reinhard, Andersson, Karl-Erik
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571845/
https://ncbi.nlm.nih.gov/pubmed/10694248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703061
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