Direct myocardial anti-ischaemic effect of GTN in both nitrate-tolerant and nontolerant rats: a cyclic GMP-independent activation of K(ATP)

1. We have recently demonstrated that glyceryl trinitrate (GTN) exerts a direct myocardial anti-ischaemic effect in both GTN-tolerant and nontolerant rats. Here we examined if this effect is mediated by GTN-derived nitric oxide (NO) and involves guanosine 3′5′ cyclic monophosphate (cyclic GMP) and A...

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Detalhes bibliográficos
Main Authors: Csont, Tamás, Szilvássy, Zoltán, Fülöp, Ferenc, Nedeianu, Saviana, Páli, Tibor, Tosaki, Árpád, Dux, László, Ferdinandy, Péter
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571777/
https://ncbi.nlm.nih.gov/pubmed/10602321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702929
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