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Nociceptin (1–7) antagonizes nociceptin-induced hyperalgesia in mice
Nociceptin and its N-terminal fragment, nociceptin (1–7), were administered intrathecally (i.t.) into conscious mice. Nociceptin (3.0 fmol) produced a significant reduction in the nociceptive thermal threshold (hyperalgesia) measured as the tail-flick and paw-withdrawal responses. Nociceptin (1–7),...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
1999
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571734/ https://ncbi.nlm.nih.gov/pubmed/10556929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702898 |
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