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Protein kinase C co-expression and the effects of halothane on rat skeletal muscle sodium channels

1. Voltage-gated Na channels, which are potential targets for general anaesthetics, are substrates for PKC, which phosphorylates a conserved site in the channel inactivation gate. We investigated the idea that PKC modulates the effect of volatile anaesthetics on Na channels via phosphorylation of th...

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Detalhes bibliográficos
Main Authors: Mounsey, J Paul, Patel, Manoj K, Mistry, Dilaawar, John, J Edward, Moorman, J Randall
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571721/
https://ncbi.nlm.nih.gov/pubmed/10556936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702877
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