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Diinosine pentaphosphate (IP(5)I) is a potent antagonist at recombinant rat P2X(1) receptors

1. The antagonist activity of a series of diinosine polyphosphates (Ip(n)I, where n=3, 4, 5) was assessed against ATP-activated inward currents at rat P2X(1–4) receptors expressed in Xenopus oocytes and studied under voltage-clamp conditions. 2. Diinosine polyphosphates were prepared by the enzymati...

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Detalhes bibliográficos
Main Authors: King, B F, Liu, M, Pintor, J, Gualix, J, Miras-Portugal, M T, Burnstock, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571720/
https://ncbi.nlm.nih.gov/pubmed/10556935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702876
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