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Characterization of the binding of [(3)H]-clobenpropit to histamine H(3)-receptors in guinea-pig cerebral cortex membranes
1. We have investigated the binding of a novel histamine H(3)-receptor antagonist radioligand, [(3)H]- clobenpropit ([(3)H]-VUF9153), to guinea-pig cerebral cortex membranes. 2. Saturation isotherms for [(3)H]-clobenpropit appeared biphasic. Scatchard plots were curvilinear and Hill plot slopes were...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571704/ https://ncbi.nlm.nih.gov/pubmed/10556922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702860 |
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