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Novel antimigraineur dotarizine releases Ca(2+) from caffeine-sensitive Ca(2+) stores of chromaffin cells
1. The novel antimigraineur, dotarizine (30 μM), increased cytosolic Ca(2+) concentration, [Ca(2+)](c), in fura-2-loaded bovine adrenal chromaffin cells. This increase was transient, reached a peak in about 2–5 min (0.53±0.07 μM; n=19) and then declined to basal levels over a further 5 min period. 2...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571692/ https://ncbi.nlm.nih.gov/pubmed/10516641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702853 |
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