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Thapsigargin-induced endothelium-dependent triphasic regulation of vascular tone in the porcine renal artery

1. To elucidate the role of thapsigargin-induced Ca(2+) entry in endothelial cells in the regulation of vascular tone, changes in Ca(2+) and force of smooth muscle were simultaneously monitored in fura-2-loaded strips of porcine renal artery. 2. During phenylephrine-induced sustained contraction, th...

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Detalhes bibliográficos
Main Authors: Ihara, Eikichi, Hirano, Katsuya, Nishimura, Junji, Nawata, Hajime, Kanaide, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571664/
https://ncbi.nlm.nih.gov/pubmed/10516650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702821
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