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21-Aminosteroids prevent the down-regulation of hepatic cytochrome P450 induced by hypoxia and inflammation in conscious rabbits

1. This study was conducted to assess whether a 21-aminosteroid, U74389G, could prevent the down-regulation of hepatic cytochrome P450 (P450) induced by acute moderate hypoxia or an inflammatory reaction. 2. The rabbits of two groups (n=6 per group) were subjected to acute moderate hypoxia (PaO(2)≈3...

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Detalhes bibliográficos
Main Authors: Galal, Ahmed, du Souich, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571640/
https://ncbi.nlm.nih.gov/pubmed/10510447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702796
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