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Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation

Alx4 and Msx2 encode homeodomain-containing transcription factors that show a clear functional overlap. In both mice and humans, loss of function of either gene is associated with ossification defects of the skull vault, although the major effect is on the frontal bones in mice and the parietal bone...

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Библиографические подробности
Главные авторы: Antonopoulou, Ileana, Mavrogiannis, Lampros A, Wilkie, Andrew O M, Morriss-Kay, Gillian M
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2004
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571319/
https://ncbi.nlm.nih.gov/pubmed/15198690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0021-8782.2004.00304.x
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