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Recovery by ascorbate of impaired nitric oxide-dependent relaxation resulting from oxidant stress in rat aorta

1. In this study we investigated the ability of ascorbate to protect nitric oxide from destruction by superoxide anion. 2. Ascorbate produced concentration-dependent relaxation of rings of rat aorta, comprising two components: the first, seen at 1–300 μM, reached a maximum of 45.3±2.8%, and was abol...

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Detalhes bibliográficos
Main Authors: Dudgeon, Sinead, Benson, David P, MacKenzie, Andrew, Paisley-Zyszkiewicz, Karen, Martin, William
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571043/
https://ncbi.nlm.nih.gov/pubmed/9831915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702120
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