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NK-3 receptors mediate enhancement of substance P release from capsaicin-sensitive spinal cord afferent terminals
1. The effects of NK-3 receptor agonists on the release of substance P-immunoreactivity (SP-LI) have been investigated using superfused rat spinal cord synaptosomes. 2. The Ca(2+)-dependent overflow of SP-LI evoked by 35 mM KCl was concentration-dependently enhanced by senktide (EC(50)=52 nM; maxima...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1998
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1571038/ https://ncbi.nlm.nih.gov/pubmed/9831894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702093 |
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