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Decline in the expression of copper/zinc superoxide dismutase in the kidney of rats with endotoxic shock: Effects of the superoxide anion radical scavenger, tempol, on organ injury

1. Endotoxaemia causes an enhanced formation of reactive oxygen species (ROS) which contribute to the multiple organ dysfunction syndrome (MODS) in septic shock. Here we investigate (i) the effects of endotoxin on the expression of two isoforms of superoxide dismutase (SOD), namely Cu/Zn-SOD (cytoso...

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Detalhes bibliográficos
Main Authors: Leach, Mary, Frank, Stefan, Olbrich, Antje, Pfeilschifter, Josef, Thiemermann, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571036/
https://ncbi.nlm.nih.gov/pubmed/9831920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702123
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