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Pharmacological characterization of endothelin-induced contraction in the guinea-pig oesophageal muscularis mucosae

1. In the oesophageal muscularis mucosae, we examined the effects of endothelin-1 (ET-1), endothelin-2 (ET-2), endothelin-3 (ET-3) and sarafotoxin S6c (SX6c) as agonists, and FR139317, BQ-123 and RES-701-1 as endothelin receptor antagonists. 2. All of the endothelins produced tonic contractions whic...

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Autors principals: Uchida, Kohsuke, Yuzuki, Rika, Kamikawa, Yuichiro
Format: Artigo
Idioma:Inglês
Publicat: 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571009/
https://ncbi.nlm.nih.gov/pubmed/9831924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702140
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