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Recombinant human alpha-2a interferon promotes an atypical process of mast cell secretion with ultrastructural features suggestive for piecemeal degranulation

Purified mast cells (MC), isolated from the rat peritoneum, were stimulated in vitro with recombinant human IFN-α 2a (rhIFN-α 2a) and studied ultrastructurally. Quantitative determination of histamine release was also performed. The following ultrastructural features were observed: (1) dilation of s...

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Main Authors: Crivellato, Enrico, Candussio, Luigi, Mallardi, Franco, Ribatti, Domenico
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570992/
https://ncbi.nlm.nih.gov/pubmed/12489762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1469-7580.2002.00116.x
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