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The UL144 gene product of human cytomegalovirus activates NFκB via a TRAF6-dependent mechanism

Molecular mimicry of cytokines and cytokine receptors is a strategy used by poxviruses and herpesviruses to modulate host immunity. The human cytomegalovirus (HCMV) UL144 gene, situated in the UL/b′ region of the viral genome, has amino-acid sequence similarity to members of the tumour necrosis fact...

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Autors principals: Poole, Emma, King, Christine A, Sinclair, John H, Alcami, Antonio
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570428/
https://ncbi.nlm.nih.gov/pubmed/16932746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601287
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