Interaction of mature CD3(+)CD4(+) T cells with dendritic cells triggers the development of tertiary lymphoid structures in the thyroid

Ectopic expression of CC chemokine ligand 21 (CCL21) in the thyroid leads to development of lymphoid structures that resemble those observed in Hashimoto thyroiditis. Deletion of the inhibitor of differentiation 2 (Id2) gene, essential for generation of CD3(–)CD4(+) lymphoid tissue–inducer (LTi) cel...

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Main Authors: Marinkovic, Tatjana, Garin, Alexandre, Yokota, Yoshifumi, Fu, Yang-Xin, Ruddle, Nancy H., Furtado, Glaucia C., Lira, Sergio A.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2006
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570377/
https://ncbi.nlm.nih.gov/pubmed/16998590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28993
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