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Genetic Exchange Between Homeologous Sequences in Mammalian Chromosomes Is Averted by Local Homology Requirements for Initiation and Resolution of Recombination
We examined the mechanism by which recombination between imperfectly matched sequences (homeologous recombination) is suppressed in mammalian chromosomes. DNA substrates were constructed, each containing a thymidine kinase (tk) gene disrupted by insertion of an XhoI linker and referred to as a “reci...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Copyright © 2006 by the Genetics Society of America
2006
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569803/ https://ncbi.nlm.nih.gov/pubmed/16816418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.060590 |
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