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Deletion Polymorphism of Disc1 Is Common to All 129 Mouse Substrains: Implications for Gene-Targeting Studies of Brain Function

We report that the Disc1 gene in all extant 129 mouse inbred substrains has a deletion, previously considered specific to the 129S6/SvEv substrain, which is predicted to abolish production of the full-length protein. This finding has implications for the study of knockout mice generated from 129-der...

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Detalhes bibliográficos
Main Authors: Clapcote, Steven J., Roder, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569715/
https://ncbi.nlm.nih.gov/pubmed/16751659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.060749
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