Statistical Analysis of Pathogenicity of Somatic Mutations in Cancer

Recent large-scale sequencing studies have revealed that cancer genomes contain variable numbers of somatic point mutations distributed across many genes. These somatic mutations most likely include passenger mutations that are not cancer causing and pathogenic driver mutations in cancer genes. Esta...

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Главные авторы: Greenman, Chris, Wooster, Richard, Futreal, P. Andrew, Stratton, Michael R., Easton, Douglas F.
Формат: Artigo
Язык:Inglês
Опубликовано: Copyright © 2006 by the Genetics Society of America 2006
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Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569711/
https://ncbi.nlm.nih.gov/pubmed/16783027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.044677
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