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Preservation and Expansion of the Primate Keratocyte Phenotype by Downregulating TGF-β Signaling in a Low-Calcium, Serum-Free Medium

PURPOSE: To demonstrate whether the original keratocyte phenotype is maintained with proliferative activity by suppressing TGF-β signaling in rhesus monkey keratocytes expanded in a serum-free and low-[Ca(2+)] medium. METHODS: Rhesus monkey keratocytes were isolated from central corneal buttons by c...

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Detalhes bibliográficos
Main Authors: Kawakita, Tetsuya, Espana, Edgar M., He, Hua, Smiddy, Robert, Parel, Jean-Marie, Liu, Chia-Yang, Tseng, Scheffer C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569676/
https://ncbi.nlm.nih.gov/pubmed/16638999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-1040
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