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Approach to risk assessment for genotoxic carcinogens based on data from the mouse skin initiation-promotion model.

Tumor induction data in the mouse skin initiation-promotion system were found to be consistent with a quadratic function where the coefficient of the linear term depended on the dose of the promoter. The model implies that the existence of promoters may be more important at low doses of the carcinog...

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Detalhes bibliográficos
Main Authors: Burns, F, Albert, R, Altshuler, B, Morris, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569213/
https://ncbi.nlm.nih.gov/pubmed/6873021
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