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Comparison of multiple vertebrate genomes reveals the birth and evolution of human exons

Orthologous gene structures in eight vertebrate species were compared on a genomic scale to detect the birth and maturation of new internal exons during the course of evolution. We found that 40% of new human exons are alternatively spliced, and most of these are cassette exons (exons that are eithe...

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Bibliografiske detaljer
Main Authors: Zhang, Xiang H.-F., Chasin, Lawrence A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569180/
https://ncbi.nlm.nih.gov/pubmed/16938881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603042103
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