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Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site

Aminopeptidase N from Escherichia coli is a major metalloprotease that participates in the controlled hydrolysis of peptides in the proteolytic pathway. Determination of the 870-aa structure reveals that it has four domains similar to the tricorn-interacting factor F3. The thermolysin-like active si...

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Detalhes bibliográficos
Main Authors: Addlagatta, Anthony, Gay, Leslie, Matthews, Brian W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569165/
https://ncbi.nlm.nih.gov/pubmed/16938892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606167103
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