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Induction of the base displacement or Z conformation in DNA by N-2-acetylaminofluorene modification

Modification of deoxyguanosine at the C(8) position by the carcinogen N-acetoxy-N-2-acetylaminofluorene (N-AcO-AAF) has been shown to result in two different conformational changes dependent on the nucleotide sequence of the modified polymer. AAF modification of random sequence DNA results in a larg...

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Bibliografiske detaljer
Main Authors: Santella, Regina M., Grunberger, Dezider
Format: Artigo
Sprog:Inglês
Udgivet: 1983
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569143/
https://ncbi.nlm.nih.gov/pubmed/6832088
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