Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation

Severe acute respiratory syndrome (SARS) coronavirus (SCoV) causes a recently emerged human disease associated with pneumonia. The 5′ end two-thirds of the single-stranded positive-sense viral genomic RNA, gene 1, encodes 16 mature proteins. Expression of nsp1, the most N-terminal gene 1 protein, pr...

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Bibliografiske detaljer
Main Authors: Kamitani, Wataru, Narayanan, Krishna, Huang, Cheng, Lokugamage, Kumari, Ikegami, Tetsuro, Ito, Naoto, Kubo, Hideyuki, Makino, Shinji
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568942/
https://ncbi.nlm.nih.gov/pubmed/16912115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603144103
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