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Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles

Myosin VI (myo6) is the only actin-based molecular motor that translocates along actin filaments toward the minus end. Myo6 participates in two steps of endocytic trafficking; it is recruited to both clathrin-coated pits and to ensuing uncoated endocytic vesicles (UCV). Although there is evidence su...

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Bibliographic Details
Main Authors: Naccache, Samia N., Hasson, Tama, Horowitz, Arie
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568917/
https://ncbi.nlm.nih.gov/pubmed/16908842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605317103
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