Alterations in epidermal biochemistry as a consequence of stage-specific genetic changes in skin carcinogenesis.

The induction of cancer on mouse skin by initiation-promotion protocols occurs through stages in which a benign squamous papilloma is an obligate precursor of squamous cell carcinoma. Activation of the Ha-ras gene is sufficient to produce the papilloma phenotype, while additional genetic changes are...

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Main Authors: Yuspa, S H, Kilkenny, A, Cheng, C, Roop, D, Hennings, H, Kruszewski, F, Lee, E, Strickland, J, Greenhalgh, D A
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568044/
https://ncbi.nlm.nih.gov/pubmed/1773799
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