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Voltage-dependent conformational changes in human Ca(2+)- and voltage-activated K(+) channel, revealed by voltage-clamp fluorometry

Large conductance voltage- and Ca(2+)-activated K(+) (BK(Ca)) channels regulate important physiological processes such as neurotransmitter release and vascular tone. BK(Ca) channels possess a voltage sensor mainly represented by the S4 transmembrane domain. Changes in membrane potential displace the...

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Main Authors: Savalli, Nicoletta, Kondratiev, Andrei, Toro, Ligia, Olcese, Riccardo
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567928/
https://ncbi.nlm.nih.gov/pubmed/16895996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601176103
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