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Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site

Epoxide hydrolases are essential for the processing of epoxide-containing compounds in detoxification or metabolism. The classic epoxide hydrolases have an α/β hydrolase fold and act via a two-step reaction mechanism including an enzyme–substrate intermediate. We report here the structure of the lim...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Arand, Michael, Hallberg, B.Martin, Zou, Jinyu, Bergfors, Terese, Oesch, Franz, van der Werf, Mariët J., de Bont, Jan A.M., Jones, T.Alwyn, Mowbray, Sherry L.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2003
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12773375/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg275
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