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Identification of IgF, a hinge-region-containing Ig class, and IgD in Xenopus tropicalis

Only three Ig isotypes, IgM, IgX, and IgY, were previously known in amphibians. Here, we describe a heavy-chain isotype in Xenopus tropicalis, IgF (encoded by C(φ)), with only two constant region domains. IgF is similar to amphibian IgY in sequence, but the gene contains a hinge exon, making it the...

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Autori principali: Zhao, Yaofeng, Pan-Hammarström, Qiang, Yu, Shuyang, Wertz, Nancy, Zhang, Xiaofeng, Li, Ning, Butler, John E., Hammarström, Lennart
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567701/
https://ncbi.nlm.nih.gov/pubmed/16877547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600291103
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