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Drosophila Rtf1 functions in histone methylation, gene expression, and Notch signaling

The Rtf1 subunit of the Paf1 complex is required for proper monoubiquitination of histone H2B and methylation of histone H3 on lysines 4 (H3K4) and 79 in yeast Saccharomyces cerevisiae. Using RNAi, we examined the role of Rtf1 in histone methylation and gene expression in Drosophila melanogaster. We...

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Библиографические подробности
Главные авторы: Tenney, Kristen, Gerber, Mark, Ilvarsonn, Anne, Schneider, Jessica, Gause, Maria, Dorsett, Dale, Eissenberg, Joel C., Shilatifard, Ali
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567682/
https://ncbi.nlm.nih.gov/pubmed/16882721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603620103
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