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Effects of zinc and cadmium on apoptotic DNA fragmentation in isolated bovine liver nuclei.

Isolated nuclei from mammalian cells contain a calcium-dependent endonuclease. The produced DNA fragmentation is a necessary step in the sequence of events resulting in apoptosis (programmed cell death). We report here that zinc and cadmium inhibit the calcium-dependent endonuclease. The essential m...

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Bibliografiske detaljer
Main Authors: Lohmann, R D, Beyersmann, D
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567406/
https://ncbi.nlm.nih.gov/pubmed/7843111
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