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A novel helper phage that improves phage display selection efficiency by preventing the amplification of phages without recombinant protein

Phage display is a widely used technology for the isolation of peptides and proteins with specific binding properties from large libraries of these molecules. A drawback of the common phagemid/helper phage systems is the high infective background of phages that do not display the protein of interest...

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Autors principals: Kramer, R. Arjen, Cox, Freek, van der Horst, Marieke, van den Oudenrijn, Sonja, Res, Pieter C. M., Bia, Judith, Logtenberg, Ton, de Kruif, John
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC156736/
https://ncbi.nlm.nih.gov/pubmed/12771223
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