The role of intercalating residues in chromosomal high-mobility-group protein DNA binding, bending and specificity

Ubiquitous high-mobility-group (HMGB) chromosomal proteins bind DNA in a non-sequence- specific fashion to promote chromatin function and gene regulation. Minor groove DNA binding of the HMG domain induces substantial DNA bending toward the major groove, and several interfacial residues contribute b...

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Bibliografische gegevens
Hoofdauteurs: Klass, Janet, Murphy, Frank V., Fouts, Susan, Serenil, Melissa, Changela, Anita, Siple, Jessica, Churchill, Mair E. A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC156723/
https://ncbi.nlm.nih.gov/pubmed/12771212
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