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Using structural motif templates to identify proteins with DNA binding function

This work describes a method for predicting DNA binding function from structure using 3-dimensional templates. Proteins that bind DNA using small contiguous helix–turn–helix (HTH) motifs comprise a significant number of all DNA-binding proteins. A structural template library of seven HTH motifs has...

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Bibliografske podrobnosti
Main Authors: Jones, Susan, Barker, Jonathan A., Nobeli, Irene, Thornton, Janet M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC156721/
https://ncbi.nlm.nih.gov/pubmed/12771208
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