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Immunohistochemical detection of aflatoxin B1-DNA adducts and hepatitis B virus antigens in hepatocellular carcinoma and nontumorous liver tissue.

Monoclonal antibodies recognizing the stable imidazole ring-opened form of the major N7-guanine aflatoxin B1-DNA adduct have been used in competitive enzyme-linked immunosorbent assays (ELISA) and indirect immunofluorescence assays to quantitate adduct levels in liver tissue. Methods were developed...

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Detalhes bibliográficos
Main Authors: Santella, R M, Zhang, Y J, Chen, C J, Hsieh, L L, Lee, C S, Haghighi, B, Yang, G Y, Wang, L W, Feitelson, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1567044/
https://ncbi.nlm.nih.gov/pubmed/8391434
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