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Development of methods to monitor exposure to 1-nitropyrene.

On the basis of 32P-postlabeling analysis, treatment of rats with 1-nitropyrene (1-NP) resulted in the formation of multiple DNA adducts in the liver, mammary glands, and peripheral lymphocytes. The one adduct resulting from nitroreduction, N-(deoxyguanosin-8-yl)-1-aminopyrene, constitutes only a mi...

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Main Authors: el-Bayoumy, K, Johnson, B, Roy, A K, Upadhyaya, P, Partian, S, Hecht, S S
格式: Artigo
語言:Inglês
出版: 1994
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566839/
https://ncbi.nlm.nih.gov/pubmed/7889855
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