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Accumulation of large non-circular forms of the chromosome in recombination-defective mutants of Escherichia coli

BACKGROUND: Double-strand breakage of chromosomal DNA is obviously a serious threat to cells because various activities of the chromosome depend on its integrity. However, recent experiments suggest that such breakage may occur frequently during "normal" growth in various organisms – from...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Handa, Naofumi, Kobayashi, Ichizo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC156651/
https://ncbi.nlm.nih.gov/pubmed/12718760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-4-5
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