Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors

Plant viral vectors allow expression of heterologous proteins at high yields, but so far, they have been unable to express heterooligomeric proteins efficiently. We describe here a rapid and indefinitely scalable process for high-level expression of functional full-size mAbs of the IgG class in plan...

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Bibliographic Details
Main Authors: Giritch, Anatoli, Marillonnet, Sylvestre, Engler, Carola, van Eldik, Gerben, Botterman, Johan, Klimyuk, Victor, Gleba, Yuri
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566189/
https://ncbi.nlm.nih.gov/pubmed/16973752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606631103
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