Differentiated effects on splanchnic homeostasis by selective and non-selective endothelin receptor antagonism in porcine endotoxaemia

1. The non-selective endothelin (ET) receptor antagonist bosentan has been shown to restore systemic and gut oxygen delivery and reverse intestinal mucosal acidosis in porcine endotoxin shock. 2. To further elucidate the specific role of the ET(A) as opposed to the ET(B) receptor and their effects i...

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Hlavní autoři: Oldner, Anders, Wanecek, Michael, Weitzberg, Eddie, Sundin, Pierre, Sollevi, Alf, Rubio, Carlos, Hellström, Per M, Alving, Kjell, Rudehill, Anders
Médium: Artigo
Jazyk:Inglês
Vydáno: 1999
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Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566181/
https://ncbi.nlm.nih.gov/pubmed/10482909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702736
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