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Treatment with inverse agonists enhances baseline atrial contractility in transgenic mice with chronic beta2-adrenoceptor activation
1. In this study, we investigate whether chronic treatment with β-adrenoceptor (βAR) ligands with inverse agonist activity enhances myocardial β(2)AR-mediated atrial tension more than neutral antagonists in transgenic mice (TG35). These mice exhibit chronic adrenoceptor activation because they posse...
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Glavni autori: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
1999
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1566118/ https://ncbi.nlm.nih.gov/pubmed/10455254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702645 |
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