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Treatment with inverse agonists enhances baseline atrial contractility in transgenic mice with chronic beta2-adrenoceptor activation

1. In this study, we investigate whether chronic treatment with β-adrenoceptor (βAR) ligands with inverse agonist activity enhances myocardial β(2)AR-mediated atrial tension more than neutral antagonists in transgenic mice (TG35). These mice exhibit chronic adrenoceptor activation because they posse...

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Bibliografski detalji
Glavni autori: Nagaraja, Savitha, Iyer, Srinivas, Liu, Xiushi, Eichberg, Joseph, Bond, Richard A
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566118/
https://ncbi.nlm.nih.gov/pubmed/10455254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702645
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